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Recombinant Heparan Sulfate Research Reagents

Heparan sulfate activity varies based on sulfate content and chain length. TEGA offers recombinant heparan sulfate (rHS) with a variety of compositions for investigation of diverse biological systems.

 

Advantages of TEGA rHS

  • Non-animal derived

  • High batch-to-batch consistency

  • Laboratory confirmed sulfate content, chain length and purity

Recombinant heparan sulfate can be purchased as single milligrams or as a value pack including five different varieties.

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Ordering

Ordering

Sampler Set

Cellular Heparan Sulfate Sampler Set
100 µg of each of the 12 variants

$850

12 x 100 µg

Combo

Cellular Heparan Sulfate Combo Pack
1 mg each - any 5 rHS variants

$2,250

5 x 1 mg

rHS01

Cellular Heparan Sulfate

~20 kDa (84 monosaccharides)

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1 mg

$500

rHS02

Cellular Heparan Sulfate

~40 kDa (166 monosaccharides)

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1 mg

$500

rHS04

Cellular Heparan Sulfate

~20 kDa (87 monosaccharides)

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1 mg

$500

rHS05

Cellular Heparan Sulfate
~35 kDa (160 monosaccharides)

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1 mg

$500

rHS06

Cellular Heparan Sulfate

~40 kDa (172 monosaccharides)

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1 mg

$500

rHS08

Cellular Heparan Sulfate
~14 kDa (60 monosaccharides)
*Contain 3-O-sulftated moieties

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1 mg

$500

rHS09

Cellular Heparan Sulfate

~20 kDa (61 monosaccharides)

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1 mg

$500

rHS10

Cellular Heparan Sulfate
>40 kDa (160 monosaccharides)

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1 mg

$500

rHS13

Cellular Heparan Sulfate
~10 kDa (40 monosaccharides)

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1 mg

$500

rHS29

Cellular Heparan Sulfate

~19 kDa (62 monosaccharides)

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1 mg

$500

rHS30

Cellular Heparin
~25 kDa (77 monosaccharides)
*Contain 3-O-sulftated moieties

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1 mg

$500

rHS37

Cellular Heparan Sulfate
~20 kDa (72 monosaccharides)

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1 mg

$500

Ordering & Shipping

  • If rHS variants are not in stock, it may take up to 2 months to produce (please inquire regarding availability)

  • rHS samples are shipped as lyopholized powders and ship at room temperature.

  • rHS samples are available for pickup, or can be shipped domestically ($50) and internationally ($200).

TEGA Recombinant Heparan Sulfate in Publications

  • Validation of Recombinant Heparan Sulphate Reagents for CNS Repair. Biology 2023. Link to article.
     

  • Biologically Derived Neoproteoglycans for Profiling Protein–Glycosaminoglycan Interactions. ACS Chem Biol. 2022.  Link to PubMed.
     

  • Multiplex genome editing of mammalian cells for producing recombinant heparin. Metabolic Engineering. 2022. Link to PubMed.
     

  • SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. Cell. 2020.  Link to PubMed.

  • ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis. Proc Natl Acad Sci U S A. 2020.  Link to PubMed.

  • Proteomics-based screening of the endothelial heparan sulfate interactome reveals that C-type lectin 14a (CLEC14A) is a heparin-binding protein. J Biol Chem. 2020.  Link to PubMed.

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